Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358939 | 0.90 | TDP1 (0.81) | TDP1L3MBTL1CES1PTPRCMAOA | |
| SCHEMBL394145 | 0.89 | TDP1 (0.80) | TDP1L3MBTL1CES1PTPRCMAOA | |
| SCHEMBL1306661 | 0.89 | TDP1 (0.80) | TDP1L3MBTL1CES1PTPRCMAOA | |
| SCHEMBL22797539 | 0.87 | TDP1 (0.77) | TDP1L3MBTL1CES1PTPRCMAOA | |
| SCHEMBL11140043 | 0.86 | TDP1 (0.75) | TDP1L3MBTL1CES1PTPRCMAOA | |
| SCHEMBL7054532 | 0.82 | TDP1 (0.69) | TDP1L3MBTL1CES1PTPRCMAOA | |
| SCHEMBL29408351 | 0.82 | CES1 (0.90) | TDP1L3MBTL1CES1MAOAMAPK1 | |
| SCHEMBL44496 | 0.82 | CES1 (0.90) | TDP1L3MBTL1CES1MAOAMAPK1 | |
| SCHEMBL29437756 | 0.82 | CES1 (0.90) | TDP1L3MBTL1CES1MAOAMAPK1 | |
| SCHEMBL11089109 | 0.81 | TDP1 (0.69) | TDP1L3MBTL1CES1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042268-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | Belupo - Lijekovi I Kozmetika D.O.O. (HR) | 2000-10-11 | — | — | EP | claimed |
| WO-1999028284-A1 | DIBENZOSUBERONE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION | BELUPO - LIJEKOVI I KOZMETIKA D.O.O. (HR) | 1999-06-10 | — | — | WO | claimed |
| WO-2020248943-A1 | NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE | 陕西莱特光电材料股份有限公司 | 2020-12-17 | — | — | WO | disclosed |
| US-10476006-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-12 | — | — | US | disclosed |
| EP-3281936-B1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| US-10431751-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-01 | — | — | US | disclosed |
| US-10424744-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-09-24 | — | — | US | disclosed |
| US-20180298279-A1 | SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | CLIPHOR TECHNOLOGY CO., LTD. (TW) | 2018-10-18 | — | — | US | disclosed |
| US-20180159045-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-06-07 | — | — | US | disclosed |
| US-20180159044-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-06-07 | — | — | US | disclosed |
| US-20180155312-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-06-07 | — | — | US | disclosed |
| EP-0214779-A1 | Tricyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-03-18 | — | — | EP | disclosed |
| US-4616023-A | CARDIOVASCULAR DISORDERS; CALCIUM BLOCKING AGENTS | MERCK & CO., INC. (US) | 1986-10-07 | — | — | US | disclosed |
| US-4160031-A | Antihistaminic and appetite stimulating 10,11-dihydro-3-carboxycyproheptadine | MERCK & CO., INC. (US) | 1979-07-03 | — | — | US | disclosed |
| US-4048223-A | 3-Dimethylsulfamoyl-5-[amino(alkyl or alkylidene)]-5H-dibenzo [a,d]cycloheptenes | MERCK & CO., INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4022902-A | APPETITE STIMULANTS AND ANTIHISTAMINES | MERCK & CO., INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
| US-3981917-A | Chemical compounds | MERCK & CO., INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3978121-A | 5H Dibenzo[a,d]cycloheptene derivatives | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
| US-3954865-A | ANTI-PARKINSON'S DISEASE, PLASTICIZERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10424744-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | TDP1 3186/4885L3MBTL1 672/4885CES1 3577/4885 |
| US-10431751-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | TDP1 3186/4885L3MBTL1 672/4885CES1 3577/4885 |
| US-10476006-B2 | Compound and organic electronic device using the same | ESR1, AOC2, PIEZO1 | TDP1 2975/4885L3MBTL1 1194/4885CES1 940/4885 |
| US-20180298279-A1 | SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | TERT, HCN1, HCN2 | TDP1 3031/4885L3MBTL1 1882/4885CES1 3873/4885 |
| US-20180155312-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SOD1, SCO2, RCOR3 | TDP1 4743/4885L3MBTL1 3581/4885CES1 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.