Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PAM | P19021 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014242 | 1.00 | DGKA (0.71) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL7549031 | 1.00 | DGKA (0.71) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL7048642 | 1.00 | DGKA (0.71) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL7052207 | 0.98 | DGKA (0.68) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL35584 | 0.87 | DGKA (0.69) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL2864987 | 0.87 | DGKA (0.69) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL8730928 | 0.87 | DGKA (0.69) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL19409845 | 0.85 | DGKA (0.71) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL2397395 | 0.85 | DGKA (0.71) | DGKAMAPTDNM1LMNAKDM4E | |
| SCHEMBL120186 | 0.85 | DGKA (0.71) | DGKAMAPTDNM1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204038-A1 | COMPOSITIONS AND KITS FOR TREATING PRURITUS AND METHODS OF USING THE SAME | Rochal Industries, LLC (US) | 2017-08-16 | — | — | EP | disclosed |
| WO-2016057789-A1 | COMPOSITIONS AND KITS FOR TREATING PRURITUS AND METHODS OF USING THE SAME | ROCHAL INDUSTRIES, LLC (US) | 2016-04-14 | — | — | WO | disclosed |
| EP-0797443-B1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | BIONERIS AB (SE) | 2003-04-23 | — | — | EP | disclosed |
| US-5760022-A | ESTER, ETHER | PERSTORP AB (SE) | 1998-06-02 | — | — | US | disclosed |
| EP-0797443-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1995019775-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIO-AVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1995-07-27 | — | — | WO | disclosed |