Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725101 | 0.84 | F10 (0.41) | F10OPRM1KLK1GAAHRH4 | |
| SCHEMBL6730030 | 0.81 | F10 (0.39) | F10OPRM1KLK1HRH4HRH3 | |
| SCHEMBL6731287 | 0.81 | F10 (0.41) | F10OPRM1KLK1HRH4HRH3 | |
| SCHEMBL6731541 | 0.80 | ALDH1A1 (0.44) | F10OPRM1KLK1HRH4HRH3 | |
| SCHEMBL6731365 | 0.80 | F10 (0.40) | F10OPRM1KLK1HRH4HRH3 | |
| SCHEMBL6730406 | 0.79 | ALDH1A1 (0.43) | F10OPRM1KLK1GAAKMT2A | |
| SCHEMBL6728616 | 0.78 | F10 (0.40) | F10OPRM1KLK1HRH4HRH3 | |
| SCHEMBL6728350 | 0.78 | OPRM1 (0.40) | F10OPRM1KLK1GAAHRH4 | |
| SCHEMBL6731706 | 0.78 | F10 (0.38) | F10OPRM1KLK1GAAHRH4 | |
| SCHEMBL6725115 | 0.77 | HRH4 (0.44) | F10KLK1GAAHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |