Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701912 | 0.74 | HTR2A (0.38) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL8642000 | 0.72 | HTR2A (0.36) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL9701863 | 0.69 | HTR2A (0.34) | HTR2A | |
| SCHEMBL31099344 | 0.69 | HTR2A (0.50) | HTR2ACYP2D6MAOAMAOBKDM4E | |
| SCHEMBL1276091 | 0.69 | HTR2A (0.50) | HTR2ACYP2D6MAOAMAOBKDM4E | |
| SCHEMBL11238143 | 0.67 | HTR2A (0.36) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL363573 | 0.67 | HTR2A (0.32) | HTR2A | |
| SCHEMBL197033 | 0.65 | HTR2A (0.41) | HTR2ACYP2D6MAOAMAOBKDM4E | |
| SCHEMBL31297722 | 0.65 | HTR2A (0.41) | HTR2ACYP2D6MAOAMAOBKDM4E | |
| SCHEMBL8693899 | 0.65 | HTR2A (0.41) | HTR2ACYP2D6MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941231-B1 | Heteroarylic-arylic diphosphines as chiral ligands | CHEMI SPA (IT) | 2003-05-02 | — | — | EP | disclosed |
| US-6153758-A | Heteroarylic-arylic diphosphines as chiral ligands | CHEMI S.P.A. (IT) | 2000-11-28 | — | — | US | disclosed |
| EP-0941231-A1 | HETEROARYLIC-ARYLIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI S.p.A. (IT) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022484-A1 | HETEROARYLIC-ARYLIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI S.P.A. (IT) | 1998-05-28 | — | — | WO | disclosed |