SCHEMBL363573

SCHEMBL363573

C1=CC2SC=Cc3ccccc3C2C=C1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7054630 0.67 HTR2A (0.38) HTR2A
SCHEMBL9701912 0.67 HTR2A (0.38) HTR2A
SCHEMBL5698322 0.67 HTR2A (0.44) HTR2A
SCHEMBL452910 0.66 ALOX5 (0.34)
SCHEMBL8642000 0.66 HTR2A (0.36) HTR2A
SCHEMBL5667976 0.64 HTR2A (0.32) HTR2A
SCHEMBL972340 0.64 HTR2A (0.32) HTR2A
SCHEMBL560766 0.64 HTR2A (0.32) HTR2A
SCHEMBL17792652 0.63 MEN1 (0.32) HTR2A
SCHEMBL24792377 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130143869-A1 USE OF A CATIONIC AMPHIPHILIC DRUG FOR THE PREPARATION OF A FORMULATION FOR THE REDUCTION OF SUBCUTANEOUS ADIPOSE TISSUE MERZ PHARMA GMBH & CO. KGAA (DE) 2013-06-06 US disclosed
EP-2593093-A1 USE OF A CATIONIC AMPHIPHILIC DRUG FOR THE PREPARATION OF A FORMULATION FOR THE REDUCTION OF SUBCUTANEOUS ADIPOSE TISSUE Merz Pharma GmbH & Co. KGaA (DE) 2013-05-22 EP disclosed
WO-2012007560-A1 USE OF A CATIONIC AMPHIPHILIC DRUG FOR THE PREPARATION OF A FORMULATION FOR THE REDUCTION OF SUBCUTANEOUS ADIPOSE TISSUE MERZ PHARMA GMBH & CO. KGAA (DE) 2012-01-19 WO disclosed