Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCL2 | P13500 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054630 | 0.72 | HTR2A (0.38) | HTR2AHTR6BRD4CCL2KDM4E | |
| SCHEMBL9701912 | 0.72 | HTR2A (0.38) | HTR2AHTR6BRD4CCL2KDM4E | |
| SCHEMBL9701863 | 0.68 | HTR2A (0.34) | HTR2A | |
| SCHEMBL363573 | 0.66 | HTR2A (0.32) | HTR2A | |
| SCHEMBL11238143 | 0.66 | HTR2A (0.36) | HTR2AHTR6KDM4ELMNATP53 | |
| SCHEMBL5058579 | 0.63 | GAA (0.35) | LMNA | |
| SCHEMBL18762880 | 0.61 | HTR2A (0.31) | HTR2A | |
| SCHEMBL33554 | 0.58 | — | — | |
| SCHEMBL29398195 | 0.58 | — | — | |
| SCHEMBL3767165 | 0.58 | MAPT (0.53) | HTR2AKDM4ELMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5711226-A | Printing method and apparatus | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-01-27 | — | — | US | disclosed |