Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2673753 | 0.85 | RECQL (0.71) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL9820174 | 0.80 | ALDH1A1 (0.57) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL31456931 | 0.78 | CYP1A2 (0.54) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL4071607 | 0.76 | RECQL (0.59) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL4074705 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL15831629 | 0.76 | HPGD (0.59) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL4066614 | 0.75 | KDM4E (0.64) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL13347720 | 0.75 | HPGD (0.54) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL15831954 | 0.75 | SMN1; SMN2 (0.51) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR | |
| SCHEMBL13310629 | 0.73 | ALDH1A1 (0.50) | CYP1A2CYP2C19SMN1; SMN2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |