Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | POLQ | O75417 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15831629 | 0.85 | HPGD (0.59) | ALDH1A1POLBHPGDGAACYP1A2 | |
| SCHEMBL13347720 | 0.84 | HPGD (0.54) | ALDH1A1POLBHPGDGAACYP1A2 | |
| SCHEMBL18556082 | 0.83 | POLB (0.48) | ALDH1A1POLBHPGDGAAKDM4E | |
| SCHEMBL3064069 | 0.83 | MAPK8 (0.49) | ALDH1A1POLBHPGDGAAKDM4E | |
| SCHEMBL20606873 | 0.83 | MAPK8 (0.59) | MAPK1 | |
| SCHEMBL7054779 | 0.80 | CYP1A2 (0.61) | ALDH1A1POLBHPGDGAACYP1A2 | |
| SCHEMBL2673753 | 0.80 | RECQL (0.71) | ALDH1A1POLBHPGDGAACYP1A2 | |
| SCHEMBL13310629 | 0.79 | ALDH1A1 (0.50) | ALDH1A1POLBHPGDGAACYP1A2 | |
| SCHEMBL5388756 | 0.79 | POLB (0.67) | ALDH1A1POLBHPGDGAACYP1A2 | |
| SCHEMBL21441534 | 0.76 | L3MBTL1 (0.48) | ALDH1A1POLBHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104876-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-12-27 | — | — | EP | disclosed |
| US-4631081-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1986-12-23 | — | — | US | disclosed |
| EP-0104876-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-04-04 | — | — | EP | disclosed |