SCHEMBL7054809

SCHEMBL7054809

COc1ccc(C2CC(=O)CC(=O)C2)cc1OC

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 13/20 0.60
PDE4B Q07343 9/20 0.60
PDE4C Q08493 9/20 0.60
PDE4D Q08499 9/20 0.60
NR3C1 P04150 1/20 0.53
GAA P10253 2/20 0.49
RAB9A P51151 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TSHR P16473 1/20 0.48
CASP1 P29466 1/20 0.48
GFER P55789 1/20 0.48
MAPT P10636 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL426375 0.93 PDE4A (0.64) PDE4APDE4BPDE4CPDE4DNR3C1
SCHEMBL29648487 0.88 PDE4A (0.59) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL30368528 0.88 PDE4A (0.66) PDE4APDE4BPDE4CPDE4DTSHR
SCHEMBL25375126 0.87 PDE4A (0.49) PDE4APDE4BPDE4CPDE4DNR3C1
SCHEMBL30368558 0.85 KDM1A (0.53) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL30368451 0.85 ALDH1A1 (0.46) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL25375025 0.85 PDE4A (0.46) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL30368709 0.85 PDE4A (0.46) PDE4APDE4BPDE4CPDE4DGAA
SCHEMBL25377288 0.85 PDE4A (0.49) PDE4APDE4BPDE4CPDE4DTSHR
SCHEMBL7052450 0.82 PDE4A (0.71) PDE4APDE4BPDE4CPDE4DNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509579-B2 Thermoplastic resin and optical lens including same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-12-30 US disclosed
CN-115996931-B Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2025-04-01 CN disclosed
US-20230399510-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-14 US disclosed
EP-4239010-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-06 EP disclosed
CN-116323753-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-06-23 CN disclosed
WO-2013068592-A1 INHIBITORS OF CYSTATHIONINE BETA SYNTHASE TO REDUCE THE NEUROTOXIC OVERPRODUCTION OF ENDOGENOUS HYDROGEN SULFIDE FONDATION JEROME LEJEUNE (FR) 2013-05-16 WO disclosed
EP-0940387-B1 PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME MITSUBISHI PHARMA CORP (JP) 2003-05-07 EP disclosed
US-6069176-A PHENYLETHANOLAMINE COMPOUNDS WITH A BETA-3 ADRENERGIC RECEPTOR STIMULATING EFFECT, USE AS A THERAPY FOR URINARY INCONTINENCE MITSUBISHI-TOKYO PHARMACEUTICALS, INC. (JP) 2000-05-30 US disclosed
EP-0940387-A1 PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME TOKYO TANABE COMPANY LIMITED (JP) 1999-09-08 EP disclosed
US-3888907-A LOWER ALKYL ESTERS OF 2-(3,4-DIMETHOXYPHENYL)-4,6-DIOXOCYCLOHEXANE CARBOXYLIC ACID HOFFMANN LA ROCHE 1975-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509579-B2 Thermoplastic resin and optical lens including same RIF1, POT1, LAS1L PDE4A 4750/4885PDE4B 4714/4885PDE4C 4785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.