Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051816 | 0.82 | FFAR1 (0.40) | CYP3A4CYP1A2MEN1KMT2AFFAR1 | |
| SCHEMBL7055462 | 0.82 | ALDH1A1 (0.46) | CYP2C9CYP2C19CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL6133051 | 0.77 | CHRNB2 (0.55) | CHRNB2CHRNA4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL4065112 | 0.75 | CHRNB2 (0.63) | CHRNB2CHRNA4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL14085289 | 0.75 | CHRNB2 (0.69) | CHRNB2CHRNA4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL5376053 | 0.75 | CHRNB2 (0.63) | CHRNB2CHRNA4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL45751 | 0.74 | KMT2A (0.42) | KMT2ALMNA | |
| SCHEMBL7453172 | 0.74 | CHRNB2 (0.51) | CHRNB2CHRNA4CYP2A6CYP2C9CYP2B6 | |
| SCHEMBL6689389 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AFFAR1LMNA | |
| SCHEMBL46934 | 0.73 | ALDH1A1 (0.38) | CYP3A4CYP1A2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303615-A2 | FERMENTATION PROCESS FOR EPOTHILONES | Kosan Biosciences, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008440-A2 | FERMENTATION PROCESS FOR EPOTHILONES | KOSAN BIOSCIENCES, INC. (US) | 2002-01-31 | — | — | WO | disclosed |