Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141386 | 0.80 | TSHR (0.40) | HTR2AHTR2CHTR2BTSHRTAAR1 | |
| SCHEMBL10779356 | 0.79 | HTR2C (0.49) | ALDH1A1SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL1023049 | 0.79 | HTR2A (0.50) | P2RX7HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL2843202 | 0.79 | TAAR1 (0.47) | RECQLHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL4292448 | 0.79 | TAAR1 (0.47) | RECQLHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL29560858 | 0.79 | TAAR1 (0.47) | RECQLHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL938227 | 0.79 | TAAR1 (0.47) | RECQLHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL29560461 | 0.79 | TAAR1 (0.47) | RECQLHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL9820912 | 0.77 | DRD2 (0.46) | HTR2C | |
| SCHEMBL13140491 | 0.76 | HTR2C (0.36) | HTR2AHTR2CHTR2BTSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611826-B1 | Processes for production of optically active epoxides | DAICEL CHEM (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5672504-A | TREATING MIXED EPOXIDE ENANTIOMORPHS WITH MICROORGANISMS TO INCREASE CONCENTRATION OF OPTICALLY PURE S-ENANTIOMORPHS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0611826-A2 | Processes for production of optically active epoxides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-24 | — | — | EP | disclosed |