Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185628 | 0.83 | ADORA1 (0.48) | ADORA1ADORA2AADORA2BTLR7HPGD | |
| SCHEMBL3181198 | 0.78 | ADORA1 (0.52) | ADORA1ADORA2AADORA2BTLR7HPGD | |
| SCHEMBL3179786 | 0.78 | ADORA1 (0.49) | ADORA1ADORA2AADORA2BTLR7HPGD | |
| SCHEMBL3175429 | 0.77 | ADORA2A (0.53) | ADORA1ADORA2AADORA2BTLR7HPGD | |
| SCHEMBL3176858 | 0.76 | ADORA1 (0.46) | ADORA1ADORA2AADORA2BTLR7PDE4A | |
| SCHEMBL3188553 | 0.69 | PDE5A (0.45) | ADORA1ADORA2AADORA2BTLR7PDE4A | |
| SCHEMBL7345938 | 0.69 | PDE5A (0.66) | ADORA1ADORA2AADORA2BTLR7PDE4A | |
| SCHEMBL13451946 | 0.68 | HPGD (0.47) | TLR7HPGDMTOR | |
| SCHEMBL3179415 | 0.68 | ALDH1A1 (0.46) | HPGDHSD17B10 | |
| SCHEMBL5227560 | 0.67 | ADORA1 (0.90) | ADORA1ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305328-A2 | MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES | Lyles, Mark B. (US) | 2003-05-02 | — | — | EP | claimed |
| WO-2002008237-A2 | MATERIALS AND METHODS FOR BINDING NUCLEIC ACIDS TO SURFACES | LYLES MARK B (US) | 2002-01-31 | — | — | WO | claimed |