Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.73 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799999 | 0.86 | PARP1 (1.00) | PARP1KCNK3KCNK9POLBSMN1; SMN2 | |
| SCHEMBL12798 | 0.86 | PARP1 (1.00) | PARP1KCNK3KCNK9POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4376573 | 0.84 | PARP1 (0.96) | PARP1KCNK3KCNK9POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5089078 | 0.84 | PARP1 (0.96) | PARP1KCNK3KCNK9POLBSMN1; SMN2 | |
| SCHEMBL1558192 | 0.82 | ALDH1A1 (0.56) | RAB9ANPC1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6099 | 0.82 | ALDH1A1 (0.56) | RAB9ANPC1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29530873 | 0.81 | POLB (0.72) | PARP1KCNK3KCNK9POLBRAB9A | |
| SCHEMBL11612584 | 0.81 | POLB (0.72) | PARP1KCNK3KCNK9POLBRAB9A | |
| Trimethylammonium SCHEMBL8962690 | 0.80 | PARP1 (0.88) | PARP1KCNK3KCNK9POLBSMN1; SMN2 | |
| M-Xylene SCHEMBL1203037 | 0.80 | PARP1 (0.88) | PARP1POLBSMN1; SMN2L3MBTL1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303574-A1 | AMIDE-BASED ANTIFREEZE CONCENTRATES AND COOLANT COMPOSITIONS CONTAINING THE SAME FOR PROTECTING MAGNESIUM AND MAGNESIUM ALLOYS | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008354-A1 | AMIDE-BASED ANTIFREEZE CONCENTRATES AND COOLANT COMPOSITIONS CONTAINING THE SAME FOR PROTECTING MAGNESIUM AND MAGNESIUM ALLOYS | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-31 | — | — | WO | disclosed |