Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | PDE4A | P27815 | 8/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056147 | 0.80 | PDE4A (0.60) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7055648 | 0.80 | PDE4A (0.66) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7058185 | 0.79 | PDE4A (0.65) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7057844 | 0.78 | PDE4A (0.68) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7051890 | 0.77 | PDE4A (0.62) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7053642 | 0.76 | PDE4A (0.72) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7055496 | 0.75 | PDE4A (0.60) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL3234394 | 0.74 | CHRM1 (0.86) | CHRM1CNR2 | |
| SCHEMBL24273575 | 0.74 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7051886 | 0.73 | PDE4A (0.62) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841929-B1 | QUINOLONES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-05-07 | — | — | EP | claimed |