Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 17/20 | 0.74 |
| ▸ | MMP2 | P08253 | 17/20 | 0.74 |
| ▸ | MMP9 | P14780 | 17/20 | 0.74 |
| ▸ | MMP13 | P45452 | 15/20 | 0.73 |
| ▸ | MMP1 | P03956 | 9/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041322 | 0.94 | MMP3 (0.84) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL8046516 | 0.94 | MMP2 (0.84) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL8039441 | 0.92 | MMP3 (0.75) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL9247824 | 0.91 | MMP3 (0.90) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL7053893 | 0.91 | MMP3 (0.90) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL7053227 | 0.89 | MMP3 (0.81) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL7052106 | 0.88 | MMP3 (0.74) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL8046789 | 0.87 | MMP3 (0.84) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL8029681 | 0.86 | MMP2 (0.85) | MMP3MMP2MMP9MMP13MMP1 | |
| SCHEMBL7055373 | 0.85 | MMP3 (1.00) | MMP3MMP2MMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979816-B1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-05-02 | — | — | EP | disclosed |
| US-6063816-A | Hydroxamic acid compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0979816-A1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-02-16 | — | — | EP | disclosed |