Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11895685 | 0.84 | CES2 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL19033096 | 0.82 | CES2 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL28912562 | 0.82 | MEN1 (0.53) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL18683483 | 0.80 | MEN1 (0.57) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7295687 | 0.80 | MEN1 (0.52) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7055992 | 0.80 | CES2 (0.47) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL19834962 | 0.80 | CES2 (0.47) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL25681638 | 0.78 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL24104761 | 0.78 | MEN1 (0.48) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL5932211 | 0.77 | TSHR (0.50) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |