Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 8/20 | 0.39 |
| ▸ | CA2 | P00918 | 8/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11895685 | 0.85 | CES2 (0.48) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL19033096 | 0.84 | CES2 (0.48) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL19834962 | 0.82 | CES2 (0.47) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL25681638 | 0.80 | MEN1 (0.48) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL7055994 | 0.80 | MEN1 (0.54) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL5932211 | 0.78 | TSHR (0.50) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL11895300 | 0.78 | TSHR (0.48) | CES2MEN1THRBHTTKMT2A | |
| SCHEMBL14256197 | 0.77 | TSHR (0.52) | CES2MEN1THRBHTTKMT2A | |
| Propane SCHEMBL9080458 | 0.77 | THRB (0.67) | CES2MEN1THRBHTTKMT2A | |
| Propane SCHEMBL27695023 | 0.77 | THRB (0.67) | CES2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |