Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 17/20 | 0.70 |
| ▸ | SLC16A1 | P53985 | 14/20 | 0.49 |
| ▸ | MCTS1 | Q9ULC4 | 8/20 | 0.47 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.46 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.46 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bindarit SCHEMBL187885 | 0.82 | SLC16A3 (1.00) | SLC16A3SLC16A1MCTS1 | |
| Bindarit SCHEMBL29387325 | 0.82 | SLC16A3 (1.00) | SLC16A3SLC16A1MCTS1 | |
| Bindarit SCHEMBL371677 | 0.81 | SLC16A3 (0.98) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL928767 | 0.81 | SLC16A3 (0.65) | SLC16A3SLC16A1RORC | |
| SCHEMBL927777 | 0.80 | SLC16A3 (0.64) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL928508 | 0.79 | SLC16A3 (0.87) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL928717 | 0.79 | SLC16A3 (0.87) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL927983 | 0.77 | SLC16A3 (0.83) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL927411 | 0.76 | SLC16A3 (0.80) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL2969591 | 0.75 | SLC16A3 (0.47) | SLC16A3SLC16A1MCTS1RORCSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429807-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA Pharma AG (DE) | 2004-06-23 | — | — | EP | claimed |
| WO-2003024489-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA PHARMA AG (DE) | 2003-03-27 | — | — | WO | claimed |