Bindarit

Bindarit

SCHEMBL187885

CC(C)(OCc1nn(Cc2ccccc2)c2ccccc12)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 15/20 1.00
MCTS1 Q9ULC4 10/20 0.55
SLC16A1 P53985 9/20 0.55
CNR1 P21554 1/20 0.49
ACHE P22303 1/20 0.49
CNR2 P34972 1/20 0.49
F2RL3 Q96RI0 1/20 0.47
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
NCOR2 Q9Y618 1/20 0.47
SSTR4 P31391 1/20 0.44
SCN8A Q9UQD0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bindarit SCHEMBL29387325 1.00 SLC16A3 (1.00) SLC16A3MCTS1SLC16A1CNR1ACHE
Bindarit SCHEMBL371677 0.99 SLC16A3 (0.98) SLC16A3MCTS1SLC16A1CNR1ACHE
SCHEMBL928717 0.93 SLC16A3 (0.87) SLC16A3MCTS1SLC16A1HDAC3HDAC1
SCHEMBL928508 0.93 SLC16A3 (0.87) SLC16A3MCTS1SLC16A1CNR1ACHE
SCHEMBL15372292 0.92 SLC16A3 (0.84) SLC16A3MCTS1SLC16A1CNR1ACHE
SCHEMBL927983 0.91 SLC16A3 (0.83) SLC16A3MCTS1SLC16A1CNR1CNR2
SCHEMBL1650741 0.91 SLC16A3 (0.83) SLC16A3MCTS1SLC16A1CNR1ACHE
SCHEMBL927364 0.90 SLC16A3 (0.81) SLC16A3MCTS1SLC16A1CNR1ACHE
SCHEMBL927459 0.90 SLC16A3 (0.81) SLC16A3MCTS1SLC16A1CNR1ACHE
SCHEMBL927411 0.89 SLC16A3 (0.80) SLC16A3MCTS1SLC16A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007636-A1 TREATING VASCULAR STENOSIS MAYO FOUND MEDICAL EDUCATION & RES (US) 2026-01-08 US claimed
US-20260007778-A1 METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES TRANSLATUM MEDICUS INC (CA) 2026-01-08 US claimed
EP-4662203-A1 BINDARIT CONJUGATES, COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES OR DISORDERS Translatum Medicus Inc. (CA) 2025-12-17 EP claimed
US-12465605-B2 Methods and materials for gender-dependent treatment of cardiovascular dysfunction MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2025-11-11 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
US-12377171-B2 Methods for treating and diagnosing blinding eye diseases Translatum Medicus Inc. (CA) 2025-08-05 US claimed
US-20250179166-A1 TREATMENT OF BRAIN METASTASIS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2025-06-05 US claimed
EP-4547286-A1 TREATING VASCULAR STENOSIS Mayo Foundation for Medical Education and Research (US) 2025-05-07 EP claimed
CN-119235817-B Anti-inflammatory nano drug-carrying system containing guanidine structure, and preparation method and application thereof 南昌大学第二附属医院 2025-03-21 CN claimed
CN-119235817-A Anti-inflammatory nano drug-carrying system containing guanidine structure, and preparation method and application thereof 南昌大学第二附属医院 2025-01-03 CN claimed
US-6319517-B1 TREHALOSE ADDED TO THE OUTSIDE OF THE LIPOSOMES ALREADY FORMED BEFORE LYOPHILIZATION; STABILITY AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2001-11-20 US claimed
CN-1255057-A Aqueous pharmaceutical composition containing active ingredient extremely poorly soluble in water ANGELINI RICERCHE SPA (IT) 2000-05-31 CN claimed
CN-1248163-A Pharmaceutical preparation containing lyophilized liposomes encapsulating a poorly water-soluble active ingredient and process for preparing the same ANGELINI RICERCHE SPA (IT) 2000-03-22 CN claimed
EP-0981332-A1 PHARMACEUTICAL PREPARATION COMPRISING LYOPHILIZED LIPOSOMES ENCAPSULATING AN ACTIVE PRINCIPLE WHICH IS HIGHLY INSOLUBLE IN WATER, AND THE PROCESS FOR PREPARING THE SAID PREPARATION AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO - A.C.R.A.F. - S.p.A. (IT) 2000-03-01 EP claimed
US-6020356-A SYNERGISTIC MIXTURE OF BINDARIT, IMMUNOSUPPRESSANT AND EXCIPIENT ANGELINI RICERCHE S.P.A. SOCIETA' CONSORTILE (IT) 2000-02-01 US claimed
EP-0973505-A1 AQUEOUS PHARMACEUTICAL COMPOSITION COMPRISING AN ACTIVE INGREDIENT WHICH IS HIGHLY INSOLUBLE IN WATER AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO - A.C.R.A.F. - S.p.A. (IT) 2000-01-26 EP claimed
WO-1998036735-A1 AQUEOUS PHARMACEUTICAL COMPOSITION COMPRISING AN ACTIVE INGREDIENT WHICH IS HIGHLY INSOLUBLE IN WATER AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. SPA (IT) 1998-08-27 WO claimed
WO-1998036736-A1 PHARMACEUTICAL PREPARATION COMPRISING LYOPHILIZED LIPOSOMES ENCAPSULATING AN ACTIVE PRINCIPLE WHICH IS HIGHLY INSOLUBLE IN WATER, AND THE PROCESS FOR PREPARING THE SAID PREPARATION AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 1998-08-27 WO claimed
EP-0858337-A2 A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTOIMMUNE DISEASES AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) 1998-08-19 EP claimed
WO-1997016185-A2 A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTOIMMUNE DISEASES ANGELINI RICERCHE S.P.A. SOCIETA' CONSORTILE (IT) 1997-05-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007778-A1 METHODS FOR TREATING AND DIAGNOSING BLINDING EYE DISEASES AGER, ALDH1A2, RBP1 SLC16A3 1633/4885MCTS1 3063/4885SLC16A1 852/4885
US-20250179166-A1 TREATMENT OF BRAIN METASTASIS CCR4, CCR1, CCR3 SLC16A3 268/4885MCTS1 166/4885SLC16A1 285/4885
US-20260007636-A1 TREATING VASCULAR STENOSIS CCL2, SELL, VCAM1 SLC16A3 102/4885MCTS1 482/4885SLC16A1 74/4885
US-12377171-B2 Methods for treating and diagnosing blinding eye diseases ALDH1A2, RBP1, RBP4 SLC16A3 4131/4885MCTS1 3508/4885SLC16A1 3716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.