Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 15/20 | 0.98 |
| ▸ | MCTS1 | Q9ULC4 | 10/20 | 0.54 |
| ▸ | SLC16A1 | P53985 | 9/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bindarit SCHEMBL29387325 | 0.99 | SLC16A3 (1.00) | SLC16A3MCTS1SLC16A1CNR1ACHE | |
| Bindarit SCHEMBL187885 | 0.99 | SLC16A3 (1.00) | SLC16A3MCTS1SLC16A1CNR1ACHE | |
| SCHEMBL928717 | 0.92 | SLC16A3 (0.87) | SLC16A3MCTS1SLC16A1HDAC3HDAC1 | |
| SCHEMBL928508 | 0.92 | SLC16A3 (0.87) | SLC16A3MCTS1SLC16A1CNR1ACHE | |
| SCHEMBL15372292 | 0.91 | SLC16A3 (0.84) | SLC16A3MCTS1SLC16A1CNR1ACHE | |
| SCHEMBL927983 | 0.90 | SLC16A3 (0.83) | SLC16A3MCTS1SLC16A1CNR1CNR2 | |
| SCHEMBL1650741 | 0.89 | SLC16A3 (0.83) | SLC16A3MCTS1SLC16A1CNR1ACHE | |
| SCHEMBL927364 | 0.89 | SLC16A3 (0.81) | SLC16A3MCTS1SLC16A1CNR1ACHE | |
| SCHEMBL927459 | 0.88 | SLC16A3 (0.81) | SLC16A3MCTS1SLC16A1CNR1ACHE | |
| SCHEMBL927411 | 0.88 | SLC16A3 (0.80) | SLC16A3MCTS1SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2409698-B1 | Use of an indazolemethoxyalkanoic acid to prepare a pharmaceutical composition | ACRAF (IT) | 2015-01-21 | — | — | EP | disclosed |
| US-8846745-B2 | Use of an indazolemethoxyalkanoic acid for reducing triglyceride, cholesterol and glucose levels | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2014-09-30 | — | — | US | disclosed |
| EP-2097080-B1 | USE OF AN INDAZOLEMETHOXYALKANOIC ACID FOR REDUCING TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS | ACRAF (IT) | 2013-02-20 | — | — | EP | disclosed |
| US-20120283307-A1 | USE OF AN INDAZOLEMETHOXYALKANOIC ACID FOR REDUCING TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2012-11-08 | — | — | US | disclosed |
| US-8198310-B2 | Use of an indazolemethoxyalkanoic acid for reducing triglyceride, cholesterol and glucose levels | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F.S.P.A. (IT) | 2012-06-12 | — | — | US | disclosed |
| EP-2409698-A1 | Use of an indazolemethoxyalkanoic acid to prepare a pharmaceutical composition | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. (IT) | 2012-01-25 | — | — | EP | disclosed |
| CN-101541323-B | Use of an indazolemethoxyalkanoic acid for reducing triglyceride, cholesterol and glucose levels | ACRAF | 2012-01-04 | — | — | CN | disclosed |
| US-20100069456-A1 | USE OF AN INDAZOLEMETHOXYALKANOIC ACID FOR REDUCING TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R. A.F. S.P.A. (IT) | 2010-03-18 | — | — | US | disclosed |
| CN-101541323-A | Use of an indazolemethoxyalkanoic acid for reducing triglyceride, cholesterol and glucose levels | ACRAF (IT) | 2009-09-23 | — | — | CN | disclosed |
| EP-2097080-A2 | USE OF AN INDAZOLEMETHOXYALKANOIC ACID FOR REDUCING TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008061671-A2 | USE OF AN INDAZOLEMETHOXYALKANOIC ACID FOR REDUCING TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283307-A1 | USE OF AN INDAZOLEMETHOXYALKANOIC ACID FOR REDUCING TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS | LIPC, PNLIP, GPR119 | SLC16A3 1443/4885MCTS1 4324/4885SLC16A1 1778/4885 |
| US-20100069456-A1 | USE OF AN INDAZOLEMETHOXYALKANOIC ACID FOR REDUCING TRIGLYCERIDE, CHOLESTEROL AND GLUCOSE LEVELS | INSR, GPR119, MTTP | SLC16A3 2333/4885MCTS1 4545/4885SLC16A1 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.