Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19237020 | 0.86 | PTPN2 (0.64) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7056886 | 0.84 | PTK2 (0.70) | MAPK10MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27384808 | 0.83 | MAPK10 (0.63) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9396580 | 0.78 | MEN1 (0.48) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14295557 | 0.76 | ALDH1A1 (0.47) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30821443 | 0.74 | MAPK10 (0.67) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL158623 | 0.73 | MAPK10 (0.51) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL4774133 | 0.73 | MAPK10 (0.51) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL21962695 | 0.72 | MAPT (0.53) | MAPK10MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2061678 | 0.72 | MEN1 (0.59) | MAPK10MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029241-A1 | CHK1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |