Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398335 | 0.87 | PKM (0.47) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11638233 | 0.85 | PTK2 (0.59) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15440489 | 0.84 | HPGD (0.53) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4063794 | 0.83 | TLR2 (0.54) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10734797 | 0.82 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10728971 | 0.80 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3798512 | 0.80 | RPS6KB1 (0.52) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31469754 | 0.80 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL19237020 | 0.78 | PTPN2 (0.64) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7056055 | 0.78 | MAPK10 (0.67) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311321-B1 | Heterocyclic compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-01-12 | — | — | EP | disclosed |
| US-4866065-A | ANTICONVULSANTS, ANXIOLYTIC AGENTS, HYPNOTICS, AND COGNITION ACTIVATORS | A/S FERROSAN (DK) | 1989-09-12 | — | — | US | disclosed |
| EP-0311321-A2 | Heterocyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-04-12 | — | — | EP | disclosed |