Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 12/20 | 0.57 |
| ▸ | SELE | P16581 | 12/20 | 0.57 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.57 |
| ▸ | CCNC | P24863 | 4/20 | 0.39 |
| ▸ | CDK8 | P49336 | 4/20 | 0.39 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797428 | 0.91 | ICAM1 (0.56) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7051473 | 0.80 | CDK8 (0.57) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7056195 | 0.73 | ICAM1 (0.81) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7051951 | 0.73 | ICAM1 (1.00) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7797418 | 0.70 | SELE (0.55) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7052567 | 0.70 | CDK8 (0.58) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7053701 | 0.70 | ICAM1 (0.58) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7057220 | 0.69 | CDK8 (0.60) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7255489 | 0.68 | ICAM1 (0.59) | ICAM1SELEVCAM1CCNCCDK8 | |
| SCHEMBL7056162 | 0.68 | ICAM1 (0.61) | ICAM1SELEVCAM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220365-A1 | Cell adhesion-inhibiting antiinflammatory compounds | STEWART ANDREW O (US) | 2003-11-27 | — | — | US | disclosed |
| US-6579882-B2 | Thieno(2,3-d)pyrimidine derivatives | ABBOTT LABORATORIES | 2003-06-17 | — | — | US | disclosed |
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ABBVIE INC. | 2001-09-06 | — | — | US | disclosed |
| US-6232320-B1 | THIENO(2,3-C)PYRIDINE AND 5H-THIENO(2,3-C)PYRAN DERIATIVES | ABBOTT LABORATORIES | 2001-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020030-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | ICAM1 1/4885SELE 16/4885VCAM1 2/4885 |
| US-20030220365-A1 | Cell adhesion-inhibiting antiinflammatory compounds | ICAM1, VCAM1, EPCAM | ICAM1 1/4885SELE 16/4885VCAM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.