Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 11/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCND2 | P30279 | 1/20 | 0.40 |
| ▸ | CCND3 | P30281 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057161 | 0.87 | KDR (0.47) | ABL1BCRMCHR1KDREGFR | |
| SCHEMBL14648633 | 0.83 | IGF1R (0.55) | KDREGFRIGF1RCDK4CDC7 | |
| SCHEMBL19476910 | 0.81 | EHMT2 (0.50) | ABL1BCRKDREGFRIGF1R | |
| SCHEMBL30367076 | 0.81 | EHMT2 (0.50) | ABL1BCRKDREGFRIGF1R | |
| SCHEMBL7052995 | 0.80 | AGER (0.60) | ABL1BCREGFR | |
| SCHEMBL12156502 | 0.75 | MCHR1 (0.53) | ABL1BCRMCHR1KDREGFR | |
| SCHEMBL19477274 | 0.72 | EHMT2 (0.52) | ABL1BCRKDREGFRIGF1R | |
| SCHEMBL19474426 | 0.71 | IGF1R (0.43) | KDREGFRIGF1RCDK4AURKA | |
| SCHEMBL6610208 | 0.71 | MCHR1 (0.63) | ABL1BCRMCHR1KDR | |
| SCHEMBL6811201 | 0.71 | MCHR1 (0.58) | MCHR1KDREGFRBIRC5BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026666-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO)-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, AS SRC KINASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |