Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 4/20 | 0.44 |
| ▸ | AGER | Q15109 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056569 | 0.87 | ABL1 (0.47) | KDREGFRABL1BCRIGF1R | |
| SCHEMBL1131631 | 0.83 | IGF1R (0.58) | KDREGFRIGF1RMEN1LMNA | |
| SCHEMBL30367076 | 0.83 | EHMT2 (0.50) | KDREGFRABL1BCRIGF1R | |
| SCHEMBL19476910 | 0.83 | EHMT2 (0.50) | KDREGFRABL1BCRIGF1R | |
| SCHEMBL7052367 | 0.80 | AGER (0.66) | KDREGFRABL1BCRESR1 | |
| SCHEMBL12156502 | 0.75 | MCHR1 (0.53) | KDREGFRABL1BCRESR1 | |
| SCHEMBL19461921 | 0.74 | EHMT2 (0.54) | KDREGFRIGF1RMEN1LMNA | |
| SCHEMBL19477274 | 0.74 | EHMT2 (0.52) | KDREGFRABL1BCRIGF1R | |
| SCHEMBL1131578 | 0.73 | CDK2 (0.68) | KDREGFRIGF1REPHB4 | |
| SCHEMBL31378722 | 0.73 | IGF1R (0.68) | KDREGFRIGF1RMCHR1EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026666-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO)-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, AS SRC KINASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |