Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18792573 | 0.75 | KDM4E (0.32) | KDM4EMAPTMMP2TSHRLMNA | |
| SCHEMBL18938808 | 0.75 | NOS3 (0.31) | HSP90AA1NOS3NOS1NOS2NPC1 | |
| Iodide SCHEMBL3908354 | 0.73 | KDM4E (0.31) | KDM4EMAPTMMP2TSHRLMNA | |
| SCHEMBL5547347 | 0.69 | — | — | |
| SCHEMBL2910235 | 0.65 | KDM4E (0.41) | KDM4EMAPTMMP2TSHRLMNA | |
| SCHEMBL9295249 | 0.65 | — | — | |
| SCHEMBL28526903 | 0.59 | ALDH1A1 (0.40) | KDM4EMAPTMMP2TSHRLMNA | |
| SCHEMBL20516698 | 0.59 | ALDH1A1 (0.40) | KDM4EMAPTMMP2TSHRLMNA | |
| SCHEMBL28420418 | 0.59 | ALDH1A1 (0.40) | KDM4EMAPTMMP2TSHRLMNA | |
| SCHEMBL14935528 | 0.59 | ALDH1A1 (0.40) | KDM4EMAPTMMP2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030198960-A1 | Signal amplifying targeted reporters for biological and chemical sensor applications | INTEGRATED NANOSYSTEMS, INC. | 2003-10-23 | — | — | US | disclosed |