SCHEMBL7056712

SCHEMBL7056712

CCOC(=O)c1[nH]c(C)c(N)c1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
HPGD P15428 7/20 0.51
ALDH1A1 P00352 8/20 0.50
KDM4E B2RXH2 5/20 0.50
GAA P10253 3/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HTT P42858 2/20 0.47
RECQL P46063 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 3/20 0.47
MAPK1 P28482 3/20 0.46
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 2/20 0.44
GLA P06280 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8053715 0.83 CYP1A2 (0.68) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL7056757 0.81 CYP1A2 (0.59) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL16504003 0.81 CYP1A2 (0.70) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL7005884 0.79 ALDH1A1 (0.50) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL28896334 0.77 CYP1A2 (0.70) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL9898080 0.76 HPGD (0.69) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL7051466 0.75 HPGD (0.50) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL2565795 0.71 CYP1A2 (1.00) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL8183536 0.70 CYP1A2 (0.43) CYP1A2CYP2C9CYP2C19HPGDALDH1A1
SCHEMBL2342953 0.69 TUBB4A (0.63) HPGDALDH1A1KDM4EGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003020877-A2 STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES PHARMACIA CORPORATION (US) 2003-03-13 WO disclosed
WO-2002004417-A1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF 4-AMINO-3-HYDROXYPYRROLE-2-CARBOXYLIC ACID PHARMACIA CORPORAION (US) 2002-01-17 WO disclosed