Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154729 | 0.81 | KDM4E (0.31) | KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL2215301 | 0.79 | MMP2 (0.35) | KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL28782535 | 0.78 | GPR35 (0.37) | KDM4EMEN1KMT2ATDP1USP2 | |
| SCHEMBL7253526 | 0.77 | NOTUM (0.40) | KDM4EMEN1KMT2ATDP1USP2 | |
| SCHEMBL31454221 | 0.75 | GPR35 (0.35) | USP2GPR35NOTUM | |
| SCHEMBL1254374 | 0.75 | GPR35 (0.46) | MEN1KMT2AUSP2GPR35NOTUM | |
| SCHEMBL22890300 | 0.71 | GRIA4 (0.38) | KDM4E | |
| SCHEMBL5154621 | 0.70 | SELL (0.34) | KDM4ETDP1GPR35 | |
| SCHEMBL19332519 | 0.69 | TSHR (0.45) | MEN1KMT2ATDP1GPR35 | |
| SCHEMBL1254367 | 0.69 | BRD4 (0.47) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020877-A2 | STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES | PHARMACIA CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |