Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604636 | 0.98 | TAAR1 (0.72) | TAAR1CHRM2AOC3IDO1SIGMAR1 | |
| SCHEMBL29263690 | 0.98 | TAAR1 (0.72) | TAAR1CHRM2AOC3IDO1SIGMAR1 | |
| SCHEMBL27842526 | 0.98 | TAAR1 (0.72) | TAAR1CHRM2AOC3IDO1SIGMAR1 | |
| SCHEMBL31689750 | 0.94 | TAAR1 (0.78) | TAAR1CHRM2AOC3IDO1SIGMAR1 | |
| SCHEMBL4860531 | 0.94 | TAAR1 (0.78) | TAAR1CHRM2AOC3IDO1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1026023 | 0.92 | TAAR1 (0.75) | TAAR1CHRM2AOC3IDO1SIGMAR1 | |
| SCHEMBL305943 | 0.86 | TAAR1 (1.00) | TAAR1AOC3IDO1SIGMAR1 | |
| SCHEMBL29350784 | 0.86 | TAAR1 (1.00) | TAAR1AOC3IDO1SIGMAR1 | |
| SCHEMBL7831226 | 0.86 | TAAR1 (0.69) | TAAR1CHRM2AOC3IDO1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11152248 | 0.84 | TAAR1 (0.96) | TAAR1AOC3IDO1SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614614-A | ANTIBIOTICS, CHEMICAL INTERMEDIATES | ROUSSEL UCLAF (FR) | 1997-03-25 | — | — | US | claimed |
| EP-0596802-B1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-03-20 | — | — | EP | claimed |
| CN-1090581-A | The preparation method of the novel derivative of erythromycin and they and as the application of medicine | ROUSSEL UCLAF (FR) | 1994-08-10 | — | — | CN | claimed |
| EP-0596802-A1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1994-05-11 | — | — | EP | claimed |
| EP-2727920-B1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2016-11-02 | — | — | EP | disclosed |
| US-8841456-B2 | 1,5-naphthyridine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20140142302-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-05-22 | — | — | US | disclosed |
| EP-2727920-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-20030181446-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-09-25 | — | — | US | disclosed |
| US-20030162777-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-08-28 | — | — | US | disclosed |
| EP-1037876-A1 | BIPHENYL DERIVATIVES AS PHARMACEUTICALS | Novartis AG (CH) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999023073-A1 | BIPHENYL DERIVATIVES AS PHARMACEUTICALS | NOVARTIS AG (CH) | 1999-05-14 | — | — | WO | disclosed |
| CN-1040876-C | New derivatives of erythromycin, their preparation process, their use as medicaments | ROUSSEL UCLAF (FR) | 1998-11-25 | — | — | CN | disclosed |
| US-5614614-A | ANTIBIOTICS, CHEMICAL INTERMEDIATES | ROUSSEL UCLAF (FR) | 1997-03-25 | — | — | US | disclosed |
| US-5527780-A | BACTERICIDES | ROUSSEL UCLAF (FR) | 1996-06-18 | — | — | US | disclosed |
| EP-0596802-B1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-03-20 | — | — | EP | disclosed |
| CN-1090581-A | The preparation method of the novel derivative of erythromycin and they and as the application of medicine | ROUSSEL UCLAF (FR) | 1994-08-10 | — | — | CN | disclosed |
| EP-0596802-A1 | Erythromycin derivatives, their process of preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1994-05-11 | — | — | EP | disclosed |
| EP-0002604-A1 | Quaternary ammonium salts, and their formulations and preparation | ELI LILLY AND COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162777-A1 | Novel N-acylated heterocycles | HTR1A, HTR1D, HTR1E | TAAR1 94/4885CHRM2 43/4885AOC3 546/4885 |
| US-20030181446-A1 | Novel N-acylated heterocycles | HTR1A, HTR1E, HTR2C | TAAR1 144/4885CHRM2 223/4885AOC3 722/4885 |
| US-20140142302-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | NRAS, RAF1, KRAS | TAAR1 3612/4885CHRM2 3219/4885AOC3 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.