Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15141549 | 0.76 | HTR2C (0.42) | SMN1; SMN2NPC1MDM2HTR2C | |
| SCHEMBL21780613 | 0.75 | KDM4E (0.44) | HPGDLMNAPDE1CPDE1BHTR2C | |
| SCHEMBL12822863 | 0.74 | OPRL1 (0.33) | PDE1CPDE1B | |
| SCHEMBL23258722 | 0.73 | MAP3K14 (0.35) | POLBTSHRSMN1; SMN2MAPTHPGD | |
| SCHEMBL28945295 | 0.73 | PTGES2 (0.41) | LMNA | |
| SCHEMBL23250685 | 0.73 | MAP3K14 (0.35) | POLBTSHRSMN1; SMN2MAPTHPGD | |
| SCHEMBL6390262 | 0.72 | HTR2C (0.50) | HTTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31401543 | 0.72 | TSHR (0.52) | POLBTSHRHTTSMN1; SMN2HPGD | |
| SCHEMBL28344077 | 0.71 | PRKAG1 (0.37) | HPGDMEN1KMT2A | |
| SCHEMBL17052374 | 0.71 | HPGD (0.40) | POLBSMN1; SMN2MAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106446-A1 | PROTECTIVE COATING COMPOSITION | LESCHENKO EVGENY EVGENIEVICH (RU) | 2004-12-09 | — | — | WO | disclosed |