Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29730737 | 0.87 | PTGES2 (0.46) | PTGES2PKMCA1CA2IDH2 | |
| SCHEMBL4159762 | 0.79 | PTGES2 (0.44) | PTGES2 | |
| SCHEMBL28328314 | 0.77 | HTR6 (0.44) | CA1CA2CA9 | |
| SCHEMBL7056849 | 0.73 | POLB (0.34) | LMNA | |
| SCHEMBL15141549 | 0.72 | HTR2C (0.42) | PKM | |
| SCHEMBL27150738 | 0.71 | HTR2C (0.59) | — | |
| SCHEMBL31618513 | 0.70 | PKM (0.40) | PTGES2PKMLMNAL3MBTL1SCN9A | |
| SCHEMBL10808580 | 0.70 | CA2 (0.52) | CA1CA2CDK2CA9 | |
| SCHEMBL16947752 | 0.70 | PTGES2 (0.49) | PTGES2CA1CA2CA9 | |
| SCHEMBL11101295 | 0.69 | PKM (0.39) | PTGES2PKMLMNASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761410-A | Pyrrolopyrimidinone compounds and application thereof | 广州必贝特医药股份有限公司 | 2022-07-15 | — | — | CN | disclosed |