SCHEMBL7056885

SCHEMBL7056885

CCOC(Cl)(Cl)C(=O)O[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7058916 0.83 ALDH1A1 (0.34)
SCHEMBL7053330 0.80 CYP4F2 (0.36) CYP4F2CYP4A11
SCHEMBL11749434 0.79 ALDH1A1 (0.42) CYP4F2CYP4A11
SCHEMBL5702342 0.76 CYP4F2 (0.35) CYP4F2CYP4A11
SCHEMBL3890704 0.74 CYP4F2 (0.34) CYP4F2CYP4A11
SCHEMBL15066109 0.74 CYP4F2 (0.38) CYP4F2CYP4A11
SCHEMBL9209755 0.73 ALDH1A1 (0.33)
SCHEMBL3371080 0.73
SCHEMBL3607696 0.71 CYP4F2 (0.36) CYP4F2CYP4A11
SCHEMBL10927347 0.68 CYP4F2 (0.38) CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006118-B1 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond DOW CORNING ASIA LTD (JP) 2003-05-07 EP disclosed
US-6175031-B1 PLATINUM-CATALYZED HYDROSILYLATION BETWEEN SIH-SUBSTITUTED SILICON COMPOUNDS AND UNSATURATED GROUP-FUNCTIONAL ORGANIC OR ORGANOSILICON COMPOUNDS IN PRESENCE OF A (ACYLOXY)-FUNCTIONAL HYDROGENSILANE COMPOUND OR ACID AND HYDRO(ALKOXY)SILANE DOW CORNING ASIA, LTD. (JP) 2001-01-16 US disclosed
US-6111126-A Method for synthesizing organosilicon compounds that contain a functional group bonded to silicon across the Si-C bond DOW CORNING ASIA, LTD. (JP) 2000-08-29 US disclosed
EP-1006118-A2 Method for synthesizing organosilicon compounds that contain a group bonded to silicon across the SI-C bond Dow Corning Asia, Ltd. (JP) 2000-06-07 EP disclosed