SCHEMBL3607696

SCHEMBL3607696

CCCC(OCC)(OCC)C(=O)O[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
THRB P10828 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3890704 0.86 CYP4F2 (0.34) CYP4F2CYP4A11THRBPKM
SCHEMBL27502077 0.80 MEN1 (0.42) CYP4F2CYP4A11MEN1MAPTKMT2A
SCHEMBL9517401 0.77 LMNA (0.33) MEN1KMT2ATHRBLMNAHSD17B10
SCHEMBL28259347 0.76 LMNA (0.41) LMNAHSD17B10
SCHEMBL703499 0.75 CYP4F2 (0.39) CYP4F2CYP4A11MEN1MAPTKMT2A
SCHEMBL5702342 0.75 CYP4F2 (0.35) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL7637389 0.74 THRB (0.49) CYP4F2CYP4A11THRBPKMHTT
SCHEMBL7637381 0.74 THRB (0.31) THRB
SCHEMBL7758101 0.73 CYP4F2 (0.42) CYP4F2CYP4A11MEN1MAPTKMT2A
SCHEMBL7758102 0.73 LMNA (0.38) CYP4F2CYP4A11MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7771521-B2 Hyperbranched polyimide-based hybrid material NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY (JP) 2010-08-10 US disclosed
EP-1792928-B1 MULTIBRANCHED POLYIMIDE HYBRID MATERIAL NAT UNIV CORP NAGOYA INST TECH (JP) 2010-03-10 EP disclosed
US-20070149759-A1 HYPERBRANCHED POLYIMIDE-BASED HYBRID MATERIAL IBIDEN CO., LTD (50%) (JP) 2007-06-28 US disclosed
EP-1792928-A1 MULTIBRANCHED POLYIMIDE HYBRID MATERIAL NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY (JP) 2007-06-06 EP disclosed