Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503711 | 0.86 | ALDH1A1 (0.40) | L3MBTL1EPHX2LMNAHDAC8 | |
| SCHEMBL5149589 | 0.85 | L3MBTL1 (0.57) | L3MBTL1PPARAEPHX2PPARGCTSS | |
| SCHEMBL20510409 | 0.83 | MEN1 (0.45) | L3MBTL1LMNA | |
| SCHEMBL22367540 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PPARAEPHX2MMP3MMP9 | |
| SCHEMBL24757322 | 0.80 | L3MBTL1 (0.53) | L3MBTL1PPARAEPHX2MMP3MMP9 | |
| SCHEMBL25310129 | 0.80 | L3MBTL1 (0.55) | L3MBTL1PPARAEPHX2MMP3MMP9 | |
| SCHEMBL24757005 | 0.80 | L3MBTL1 (0.55) | L3MBTL1PPARAEPHX2MMP3MMP9 | |
| SCHEMBL17501963 | 0.80 | MEN1 (0.49) | L3MBTL1LMNA | |
| SCHEMBL26698987 | 0.80 | L3MBTL1 (0.46) | L3MBTL1PPARAEPHX2MMP3MMP9 | |
| SCHEMBL16672795 | 0.79 | L3MBTL1 (0.53) | L3MBTL1PPARAPPARGCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056475-B1 | DENDRIMERIC FULLERENE DERIVATIVES, METHOD FOR PRODUCING SAME AND THEIR USE AS NEUROPROTECTORS | SIEMENS AXIVA GMBH & CO KG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6506928-B1 | Derivative in which fullerene is linked to at least one dendron having at least one protic group which imparts water solubility | SIEMENS AXIVA GMBH & CO. KG (DE) | 2003-01-14 | — | — | US | disclosed |