Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615554 | 0.89 | TSHR (0.52) | TSHRTHRBALDH1A1GLO1POLB | |
| SCHEMBL11412289 | 0.83 | TSHR (0.48) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL15007610 | 0.83 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2038378 | 0.83 | THRB (0.48) | TSHRTHRBALDH1A1GLO1POLB | |
| SCHEMBL472711 | 0.81 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL10701490 | 0.80 | TSHR (0.46) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5654625 | 0.79 | TSHR (0.52) | TSHRTHRBALDH1A1GLO1POLB | |
| SCHEMBL1636583 | 0.79 | TSHR (0.52) | TSHRTHRBALDH1A1GLO1POLB | |
| SCHEMBL1636584 | 0.79 | TSHR (0.52) | TSHRTHRBALDH1A1GLO1POLB | |
| SCHEMBL19350263 | 0.79 | TSHR (0.48) | TSHRTHRBALDH1A1GLO1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305297-A1 | BENZOTRIAZOLES CONTAINING ALPHA-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-6392056-B1 | FOR THERMOPLASTIC RESINS | CIBA SPECIALTY CHEMICAL CORPORATION | 2002-05-21 | — | — | US | disclosed |
| WO-2002012205-A1 | BENZOTRIAZOLES CONTAINING α-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |