Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL1873140 | 0.91 | LMNA (0.43) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL5688808 | 0.82 | FOLH1 (0.45) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL8040181 | 0.82 | CYP2C9 (0.48) | ALDH1A1GAAL3MBTL1 | |
| SCHEMBL8755755 | 0.81 | RNPEP (0.48) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL14404929 | 0.81 | LMNA (0.51) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL5179360 | 0.81 | RNPEP (0.48) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL149342 | 0.81 | RNPEP (0.48) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL5179354 | 0.81 | RNPEP (0.48) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL3869337 | 0.81 | LMNA (0.51) | LMNAFOLH1RNPEPALDH1A1GAA | |
| SCHEMBL3869335 | 0.81 | LMNA (0.51) | LMNAFOLH1RNPEPALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979816-B1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-05-02 | — | — | EP | disclosed |
| EP-0979816-A1 | Hydroxamic acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-02-16 | — | — | EP | disclosed |