Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70575 | 0.88 | KMT2A (0.56) | KDM4EHPGDALDH1A1MAPK1KMT2A | |
| SCHEMBL1974763 | 0.85 | KDM4E (0.51) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL2654173 | 0.85 | KMT2A (0.54) | KDM4EHPGDALDH1A1MAPK1KMT2A | |
| SCHEMBL698811 | 0.84 | ALDH1A1 (0.51) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL25304281 | 0.83 | KMT2A (0.51) | KDM4EHPGDALDH1A1GAAMAPK1 | |
| SCHEMBL3977005 | 0.83 | ALDH1A1 (0.55) | KDM4EHPGDALDH1A1GAAMAPK1 | |
| SCHEMBL28412622 | 0.81 | KMT2A (0.50) | KDM4EHPGDALDH1A1MAPK1KMT2A | |
| SCHEMBL30002631 | 0.81 | ALDH1A1 (0.49) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL5239795 | 0.80 | MAPK8 (0.51) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL25261430 | 0.80 | HPGD (0.49) | KDM4EHPGDALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115821578-A | Antistatic wear-resistant carpet and preparation method thereof | 杨晓光 | 2023-03-21 | — | — | CN | claimed |
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2025-02-27 | — | — | US | disclosed |
| EP-4452929-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | Immunic AG (DE) | 2024-10-30 | — | — | EP | disclosed |
| CN-118382610-A | DHODH inhibitors containing carboxylic acid bioisosteres | 埃慕尼克股份公司 | 2024-07-23 | — | — | CN | disclosed |
| US-20240199535-A1 | DEUTERATED DHODH INHIBITORS | IMMUNIC AG (DE) | 2024-06-20 | — | — | US | disclosed |
| EP-4320100-A1 | DEUTERATED DHODH INHIBITORS | Immunic AG (DE) | 2024-02-14 | — | — | EP | disclosed |
| CN-117321035-A | Deuterated DHODH inhibitors | 埃慕尼克股份公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |
| CN-115821578-A | Antistatic wear-resistant carpet and preparation method thereof | 杨晓光 | 2023-03-21 | — | — | CN | disclosed |
| US-20140221422-A1 | NOVEL THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8703795-B2 | Thienopyridine compounds, and methods of use thereof | FIBROGEN, INC. (US) | 2014-04-22 | — | — | US | disclosed |
| EP-1866318-B1 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN INC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-7511070-B2 | Compounds and therapies for the prevention of vascular and non-vascular pathologies | PONIARD PHARMACEUTICALS, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| EP-1866318-A2 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006094292-A2 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. (US) | 2006-09-08 | — | — | WO | disclosed |
| US-20060199836-A1 | Novel thienopyridine compounds, and methods of use thereof | FIBROGEN, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-0267794-B1 | PROCESS FOR PREPARING POLYOLEFINS | Nippon Petrochemicals Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0267794-A2 | Process for preparing polyolefins | Nippon Petrochemicals Co., Ltd. (JP) | 1988-05-18 | — | — | EP | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221422-A1 | NOVEL THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | HIF1AN, HIF1A, EGLN2 | KDM4E 679/4885HPGD 21/4885ALDH1A1 488/4885 |
| US-20060199836-A1 | Novel thienopyridine compounds, and methods of use thereof | HIF1AN, HIF1A, EGLN2 | KDM4E 679/4885HPGD 21/4885ALDH1A1 488/4885 |
| US-20250066290-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | DHODH, DBH, DOHH | KDM4E 2435/4885HPGD 66/4885ALDH1A1 35/4885 |
| US-20240199535-A1 | DEUTERATED DHODH INHIBITORS | DHODH, DBH, QDPR | KDM4E 1617/4885HPGD 34/4885ALDH1A1 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.