Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 13/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058602 | 0.94 | MEN1 (0.49) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7050099 | 0.90 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7059006 | 0.89 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7058698 | 0.89 | MAPT (0.42) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7060834 | 0.89 | MAPT (0.39) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7054997 | 0.89 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL6052235 | 0.89 | MEN1 (0.51) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7054601 | 0.89 | MCHR1 (0.43) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7060964 | 0.89 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1NPSR1RXFP1 | |
| SCHEMBL7057946 | 0.89 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1NPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |