Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 5/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058692 | 0.94 | ALDH1A1 (0.41) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7057769 | 0.94 | EGFR (0.39) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7060964 | 0.93 | ALDH1A1 (0.44) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7054601 | 0.91 | MCHR1 (0.43) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7050099 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7060834 | 0.90 | MAPT (0.39) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7058698 | 0.90 | MAPT (0.42) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7053934 | 0.90 | NR1H4 (0.40) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7054997 | 0.90 | ALDH1A1 (0.40) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7057946 | 0.90 | ALDH1A1 (0.40) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | claimed |