SCHEMBL7057702

SCHEMBL7057702

CC(C)CC([NH])C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,2,3-Trimethylbutane SCHEMBL11528678 0.69 TSHR (0.39) ALDH1A1TSHRMAPK1
SCHEMBL276865 0.67
SCHEMBL598944 0.67 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1
SCHEMBL5933072 0.67
SCHEMBL3721888 0.67 ALDH1A1 (0.32) ALDH1A1TSHRMAPK1
SCHEMBL103448 0.65
SCHEMBL7977298 0.65 TSHR (0.41) ALDH1A1TSHRMAPK1
SCHEMBL11488625 0.65 ALDH1A1 (0.30) ALDH1A1TSHRMAPK1
SCHEMBL3160241 0.65
SCHEMBL4109447 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994108-B1 PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES ZERIA PHARM CO LTD (JP) 2003-05-14 EP disclosed
US-6197970-B1 REACTING WITH SECONDARY OR TERTIARY AMINE; DEBLOCKING, DEPROTECTING ZERIA PHARMACEUTICAL CO., LTD. (JP) 2001-03-06 US disclosed
EP-0994108-A1 PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES ZERIA PHARMACEUTICAL CO., LTD. (JP) 2000-04-19 EP disclosed