SCHEMBL7057713

SCHEMBL7057713

CN(CCC(C)(C)CO)Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.53
PRMT6 Q96LA8 1/20 0.53
PRMT8 Q9NR22 1/20 0.53
SIGMAR1 Q99720 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 4/20 0.44
TSHR P16473 3/20 0.44
TMEM97 Q5BJF2 1/20 0.44
MAOB P27338 2/20 0.43
LMNA P02545 2/20 0.43
USP2 O75604 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAOA P21397 1/20 0.43
PYCR1 P32322 1/20 0.43
BLM P54132 1/20 0.42
RIPK1 Q13546 1/20 0.41
AOC3 Q16853 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270829 0.82 CARM1 (0.47) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
SCHEMBL4478771 0.82 CARM1 (0.56) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
SCHEMBL16247246 0.82 CARM1 (0.60) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
SCHEMBL7057716 0.81 CARM1 (0.51) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
SCHEMBL16039984 0.78 CARM1 (0.51) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
SCHEMBL135868 0.77 CARM1 (0.64) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
SCHEMBL7055109 0.77 CARM1 (0.75) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
Hydrochloric Acid SCHEMBL6509438 0.76 CARM1 (0.62) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
Bromide SCHEMBL28943059 0.76 CARM1 (0.62) CARM1PRMT6PRMT8SIGMAR1SMN1; SMN2
SCHEMBL21991112 0.75 SIGMAR1 (0.60) CARM1PRMT6PRMT8SIGMAR1TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0955806-B1 BIOACTIVE COMPOUNDS US AGRICULTURE (US) 2003-05-14 EP claimed
EP-0955806-A4 BIOACTIVE COMPOUNDS US AGRICULTURE (US) 2000-05-31 EP claimed
EP-0955806-A1 BIOACTIVE COMPOUNDS THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE (US) 1999-11-17 EP claimed
WO-1997031529-A1 BIOACTIVE COMPOUNDS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1997-09-04 WO claimed
EP-0955806-B1 BIOACTIVE COMPOUNDS US AGRICULTURE (US) 2003-05-14 EP disclosed
EP-0955806-A4 BIOACTIVE COMPOUNDS US AGRICULTURE (US) 2000-05-31 EP disclosed
EP-0955806-A1 BIOACTIVE COMPOUNDS THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE (US) 1999-11-17 EP disclosed
WO-1997031529-A1 BIOACTIVE COMPOUNDS THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1997-09-04 WO disclosed