Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.63 |
| ▸ | DRD2 | P14416 | 6/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057852 | 0.88 | DRD3 (0.56) | DRD3DRD2DRD4HTR1AADRA1D | |
| SCHEMBL10724020 | 0.78 | MAPT (0.75) | DRD3DRD2NPC1RAB9AMAPT | |
| SCHEMBL7055272 | 0.77 | CCR3 (0.68) | DRD3DRD2DRD4HTR1ACCR3 | |
| SCHEMBL20922354 | 0.75 | POLB (0.61) | DRD3DRD4CCR3NPC1RAB9A | |
| SCHEMBL3124560 | 0.73 | POLB (0.81) | NPC1RAB9AMAPTPOLB | |
| SCHEMBL229190 | 0.72 | CYP2C9 (0.59) | DRD3DRD2DRD4HTR1AADRA1D | |
| Hydrochloric Acid SCHEMBL8820560 | 0.72 | POLB (0.61) | DRD4HTR1ACCR3MAPTPOLB | |
| SCHEMBL9843330 | 0.72 | HTR1A (0.88) | DRD3DRD2DRD4HTR1AADRA1D | |
| SCHEMBL9489987 | 0.72 | NPC1 (1.00) | NPC1RAB9APOLB | |
| SCHEMBL11758269 | 0.72 | NPC1 (1.00) | NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |