Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.68 |
| ▸ | DRD4 | P21917 | 11/20 | 0.62 |
| ▸ | DRD2 | P14416 | 10/20 | 0.62 |
| ▸ | DRD3 | P35462 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119593 | 0.83 | CCR3 (0.55) | CCR3DRD2DRD3 | |
| SCHEMBL7057852 | 0.82 | DRD3 (0.56) | CCR3DRD4DRD2DRD3POLB | |
| SCHEMBL4521840 | 0.81 | DRD4 (0.77) | DRD4DRD2DRD3HTR2AHTR1A | |
| SCHEMBL18502056 | 0.81 | CHRM4 (0.63) | CCR3DRD2DRD3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6402140 | 0.79 | CCR3 (0.71) | CCR3DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL27570348 | 0.79 | CCR3 (0.71) | CCR3DRD4DRD2 | |
| SCHEMBL28823593 | 0.77 | CCR3 (0.61) | CCR3DRD4DRD2DRD3SLC6A2 | |
| SCHEMBL7057804 | 0.77 | DRD3 (0.63) | CCR3DRD4DRD2DRD3POLB | |
| SCHEMBL4500805 | 0.77 | PABPC1 (0.76) | DRD2 | |
| SCHEMBL10723885 | 0.76 | DRD2 (0.72) | CCR3DRD4DRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |