Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150282 | 0.91 | HDAC8 (0.42) | HDAC8ACHEPOLBPABPC1KDM4E | |
| SCHEMBL29461432 | 0.91 | HDAC8 (0.42) | HDAC8ACHEPOLBPABPC1KDM4E | |
| Water SCHEMBL29558803 | 0.89 | HDAC8 (0.41) | HDAC8ACHEPOLBPABPC1KDM4E | |
| Water SCHEMBL869251 | 0.89 | HDAC8 (0.41) | HDAC8ACHEPOLBPABPC1KDM4E | |
| SCHEMBL1560289 | 0.89 | HDAC8 (0.41) | HDAC8ACHEPOLBSMN1; SMN2 | |
| Water SCHEMBL8976458 | 0.88 | HDAC8 (0.40) | HDAC8ACHEPOLBSMN1; SMN2 | |
| SCHEMBL7057931 | 0.84 | HDAC8 (0.44) | HDAC8ACHEPOLBPABPC1KDM4E | |
| SCHEMBL12223395 | 0.83 | HDAC8 (0.41) | HDAC8ACHEPOLBPABPC1KDM4E | |
| SCHEMBL17123054 | 0.78 | HDAC8 (0.46) | HDAC8ACHEPOLBPABPC1KDM4E | |
| SCHEMBL29356904 | 0.78 | ALDH1A1 (0.48) | HDAC8ACHEPOLBPABPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028739-A2 | COMPOSITION FOR PREVENTING OR TREATING HYPERLIPIDEMIA OR HYPERGLYCEMIA COMPRISING A POLYMER OR ITS SALT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-04-10 | — | — | WO | disclosed |
| WO-2002032974-A2 | POLYMER AND ITS USE FOR THE TREATMENT AND/OR PREVENTION OF HYPERPHOSPHOREMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-25 | — | — | WO | disclosed |