Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | GFER | P55789 | 1/20 | 0.73 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | IKBKB | O14920 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059499 | 0.85 | GAA (0.73) | GAAMAPTGFERCHEK1ALOX15 | |
| SCHEMBL7057166 | 0.83 | GAA (0.75) | GAAMAPTGFERCHEK1ALOX15 | |
| SCHEMBL7055239 | 0.81 | CHEK1 (1.00) | CHEK1IKBKBJAK2 | |
| SCHEMBL15960089 | 0.81 | GAA (0.75) | GAAMAPTGFERALOX15ALDH1A1 | |
| SCHEMBL1062225 | 0.80 | GAA (1.00) | GAAMAPTGFERALOX15ALDH1A1 | |
| SCHEMBL8290620 | 0.79 | GAA (0.74) | GAAMAPTGFERCHEK1ALOX15 | |
| SCHEMBL3510525 | 0.79 | IKBKB (1.00) | GAAMAPTGFERALOX15ALDH1A1 | |
| SCHEMBL20915155 | 0.78 | GAA (0.72) | GAAMAPTGFERALOX15ALDH1A1 | |
| SCHEMBL1563613 | 0.77 | GAA (1.00) | GAAMAPTGFERALOX15ALDH1A1 | |
| SCHEMBL4057174 | 0.76 | ADORA1 (1.00) | GAAMAPTGFERALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029241-A1 | CHK1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |