Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | GFER | P55789 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.67 |
| ▸ | IKBKB | O14920 | 2/20 | 0.67 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | JAK1 | P23458 | 1/20 | 0.59 |
| ▸ | TYK2 | P29597 | 1/20 | 0.59 |
| ▸ | JAK3 | P52333 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054417 | 0.85 | TUBB4A (0.58) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL7058046 | 0.83 | GAA (0.73) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL7059499 | 0.83 | GAA (0.73) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL20915155 | 0.82 | GAA (0.72) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL15960089 | 0.82 | GAA (0.75) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL1062225 | 0.82 | GAA (1.00) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL1563613 | 0.81 | GAA (1.00) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL4057174 | 0.81 | ADORA1 (1.00) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL8290620 | 0.81 | GAA (0.74) | GAAMAPTGFERALDH1A1HPGD | |
| SCHEMBL3510525 | 0.80 | IKBKB (1.00) | GAAMAPTGFERALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029241-A1 | CHK1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |