Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 17/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | CDK9 | P50750 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656847 | 0.85 | SYK (0.59) | SYKCCNT1CCNE1CDK2CDK9 | |
| R-112 SCHEMBL31294216 | 0.79 | SYK (1.00) | SYKAURKA | |
| R-112 SCHEMBL655935 | 0.79 | SYK (1.00) | SYKAURKA | |
| R-112 SCHEMBL29360016 | 0.79 | SYK (1.00) | SYKAURKA | |
| SCHEMBL657057 | 0.75 | SYK (0.65) | SYKAURKA | |
| SCHEMBL656571 | 0.75 | SYK (0.65) | SYKAURKA | |
| SCHEMBL657501 | 0.75 | SYK (0.65) | SYKAURKA | |
| SCHEMBL12567975 | 0.75 | SYK (0.85) | SYKAURKA | |
| SCHEMBL654934 | 0.74 | SYK (0.59) | SYKAURKA | |
| SCHEMBL656716 | 0.74 | SYK (0.59) | SYKCCNT1CCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029902-A1 | Antiinflamamtory agents | MIDCAP FINANCIAL TRUST | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029902-A1 | Antiinflamamtory agents | FCER2, FCGR1A, HNMT | SYK 251/4885CCNT1 3177/4885CCNE1 3365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.