SCHEMBL7058359

SCHEMBL7058359

CC(C)(c1cc(Br)c(OCCOCCO)c(Br)c1)c1cc(Br)c(OCCOCCO)c(Br)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
CYP3A4 P08684 2/20 0.43
ALOX15 P16050 2/20 0.43
ALOX12 P18054 2/20 0.43
HSD17B10 Q99714 2/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
RECQL P46063 1/20 0.43
HIF1A Q16665 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KLK1 P06870 1/20 0.38
CHEK1 O14757 1/20 0.38
DAPK3 O43293 1/20 0.38
RET P07949 1/20 0.38
PDGFRB P09619 1/20 0.38
PIM1 P11309 1/20 0.38
PDGFRA P16234 1/20 0.38
KDR P35968 1/20 0.38
MAPK8 P45983 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25899 0.90 ALDH1A1 (0.54) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL10990403 0.85 ALDH1A1 (0.53) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL13964548 0.84 ALDH1A1 (0.49) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL17206840 0.84 ALOX15 (0.61) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL13964546 0.84 ALDH1A1 (0.49) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL11765295 0.83 ALDH1A1 (0.51) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL5171572 0.81 ALDH1A1 (0.47) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL11519696 0.81 KMT2A (0.47) ALDH1A1TSHRKLK1KMT2ALMNA
SCHEMBL13964547 0.81 ALDH1A1 (0.45) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10
SCHEMBL1835076 0.80 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15ALOX12HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1449871-B1 Thermoplastic polyester-based flame-retardant resin composition and molded products thereof MITSUBISHI ENG PLASTICS CORP (JP) 2015-01-14 EP disclosed
US-20040176511-A1 Thermoplastic polyester-based flame-retardant resin composition and molded products thereof MITSUBISHI ENGINEERING-PLASTICS CORPORATION 2004-09-09 US disclosed
EP-1449871-A2 Thermoplastic polyester-based flame-retardant resin composition and molded products thereof Mitsubishi Engineering-Plastics Corporation (JP) 2004-08-25 EP disclosed