Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7057506 | 0.91 | KMT2A (0.42) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL17050154 | 0.86 | KMT2A (0.38) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL3469723 | 0.83 | KMT2A (0.58) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL24029264 | 0.81 | MPO (0.55) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL7055279 | 0.81 | MPO (0.55) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL24029263 | 0.81 | MPO (0.55) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL7057350 | 0.81 | KDM4E (0.46) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL31320223 | 0.78 | NPSR1 (0.61) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL7056204 | 0.78 | LMNA (0.50) | KMT2AMEN1KDM4EALOX12ALDH1A1 | |
| SCHEMBL2459826 | 0.78 | NPSR1 (0.61) | KMT2AMEN1KDM4EALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176314-A1 | Compounds for the treatment of pain | H. LUNDBECK A/S (DK) | 2003-09-18 | — | — | US | disclosed |
| US-20030139431-A1 | Guanidines which are agonist/antagonist ligands for neuropeptide FF (NPFF) receptors | H. LUNDBECK A/S (DK) | 2003-07-24 | — | — | US | disclosed |
| WO-2003026657-A1 | COMPOUNDS FOR THE TREATMENT OF PAIN | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176314-A1 | Compounds for the treatment of pain | NPFFR2, NPFFR1, OPRL1 | KMT2A 2310/4885MEN1 4788/4885KDM4E 4560/4885 |
| US-20030139431-A1 | Guanidines which are agonist/antagonist ligands for neuropeptide FF (NPFF) receptors | NPFFR1, NPFFR2, SSTR3 | KMT2A 3563/4885MEN1 3885/4885KDM4E 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.