Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21819026 | 0.87 | AURKA (0.45) | AURKAPARP1FEN1MAP2K1ADORA2A | |
| SCHEMBL15175716 | 0.81 | NR4A2 (0.60) | AURKAPARP1FEN1MAP2K1ALDH1A1 | |
| SCHEMBL27690047 | 0.81 | AURKA (0.40) | AURKAPARP1FEN1MAP2K1ADORA2A | |
| SCHEMBL9696279 | 0.80 | AURKA (0.45) | AURKAPARP1FEN1MAP2K1ADORA2A | |
| SCHEMBL2978600 | 0.79 | COMT (0.50) | AURKAPARP1FEN1ALDH1A1BRD4 | |
| SCHEMBL15173373 | 0.77 | NR4A2 (0.44) | AURKAPARP1FEN1MAP2K1ALDH1A1 | |
| SCHEMBL7064351 | 0.75 | ADORA3 (0.41) | PARP1ADORA2AADORA1ALDH1A1NPC1 | |
| SCHEMBL1559343 | 0.73 | NR4A2 (0.63) | ALDH1A1NPC1RAB9ANR4A2PKM | |
| SCHEMBL1714222 | 0.72 | KMT2A (0.47) | AURKAPARP1FEN1MAP2K1ADORA2A | |
| SCHEMBL7976276 | 0.72 | KDM4E (0.46) | AURKAPARP1FEN1MAP2K1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181463-A1 | Antiviral azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181463-A1 | Antiviral azaindole derivatives | ZC3HAV1, MAVS, AZI2 | AURKA 1380/4885PARP1 278/4885FEN1 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.